Nolvadex is a medication used in the treatment of estrogen receptor-positive breast cancer, specifically, hormone receptor-positive breast cancer in postmenopausal women. It is also prescribed in postmenopausal women with hormone receptor-positive breast cancer who have an advanced disease.
Nolvadex works by inhibiting the growth of estrogen receptors, thus blocking the production of oestrogen in the body. Nolvadex is a selective and potent inhibitor of aromatase, which is responsible for the conversion of androgens into estrogens. It reduces the production of estrogen in breast tissue, leading to better breast health.
Nolvadex is primarily used in the management of estrogen receptor-positive breast cancer and other hormone receptor-positive breast cancer types. It is also prescribed for the treatment of advanced breast cancer and hormone receptor-positive breast cancer in postmenopausal women. It is also used to reduce the risk of endometrial cancer and ovarian cancer.
For the treatment of hormone receptor-positive breast cancer in postmenopausal women, the recommended dosage is one Nolvadex tablet, taken orally.
For the treatment of postmenopausal women with estrogen-dependent breast cancer, the recommended dosage is one daily Nolvadex tablet, taken orally.
Nolvadex may cause side effects such as:
In rare cases, Nolvadex may have other effects such as:
Patients with breast cancer should be aware of the potential risks associated with Nolvadex, including liver disease, which may be a source of the medication. It is important to inform the doctor about any existing medical conditions, especially if they are being treated at home. Regular monitoring of liver function tests is recommended when using Nolvadex.
Nolvadex may interact with other medications, including blood pressure medications, certain antibiotics, and certain medicines used to treat cancer. It is important to inform the doctor about any current medicines and supplements that may interact with Nolvadex.
It is important to inform the doctor if you are pregnant or breastfeeding, as this can affect the effectiveness of Nolvadex. The medication should be taken at the same time each day to ensure that it remains effective in treating estrogen receptor-positive breast cancer in postmenopausal women.
It is also important to inform the doctor if you have any allergies to any medications, especially those containing acetate.
Inform the doctor if you are taking any of the following drugs:
Nolvadex should be avoided during pregnancy or breastfeeding due to the increased risk of birth defects. Nolvadex may cause harm to the fetus, especially during early life. Therefore, it is important to discuss any existing medications with the doctor to avoid potential interactions and complications.
Idelalisib
It is contraindicated to use this medicine because the use of idelalisib decreases the effect of tamoxifen by affecting its hepatic and intestinal enzymes
Bosutinib
Use alternative drug because the use of tamoxifen increases the level of bosutinib by P-glycoprotein efflux transporter
Mefloquine
Use alternative drugs because the use of mefloquine increases the toxicity of tamoxifen by QTc interval
Cannabidiol
Therapy should be administered with caution because the use of cannabidiol increases the effect of tamoxifen by decreasing its metabolism
Do not take tamoxifen along with soy products because soy stimulates the growth of tumor cells in the breast and also interferes with the action of tamoxifen.
Pulmonary embolism
It is contraindicated to use this medicine in women who are with a history of deep vein thrombosis because the use of tamoxifen increases the incidence of thromboembolic events including deep vein thrombosis,
Endometrial dysplasia
Therapy should be administered with caution in patients with a history of gynecological abnormalities because the use of tamoxifen changes the endometrium such as hyperplasia, polyps, and endometrial cancer.
Hepatic dysfunction
Therapy should be administered with caution in patients with a history of hepatic function because the use of tamoxifen alter the liver enzymes and cause severe hepatic injuries such as fatty liver, cholestasis, hepatitis, and hepatic necrosis.
Disease Interaction| Metabolism | Usroversial use | Action |
|---|---|---|
| Orlistat | Not a controlled drug use? Orlistat is meant for weight loss, and it blocks fat absorption in the diet | Orlistat is available in a weight-loss capsule and is used along with a low-calorie, low-fat diet |
| Actinomycin 1 mg | Weight loss weight loss weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight lose weight weight loss weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight weight | |
| 1 mg | ||
| Abemacicranast | Abemacicranast is used along with breast-feeding because it lowers the absorption of tamoxifen by the breast and also increases the metabolism of tamoxifen by the liver | Abemacicranast is available in a weight-loss capsule and is used along with a low-calorie, low-fat diet. |
This medicine is used for the treatment of endometriosis. It decreases the effect of tamoxifen which is used to treat breast and endometrial cancer. It also increases the absorption of tamoxifen in the diet. Therefore it is used along with a low-calorie, low-fat diet. It is not recommended for use in women who are with a history of gynecological abnormalities because the use of tamoxifen is at least in breast-feeding. It is also not recommended for use in children.
/image/nolvadex-10mg.jpg{"kid = "kid+5"}Orlistat helps in controlling the body weight.
NOLVADEX contains Tamoxifen which belongs to the group of medicines called Anti-estrogen agents. It is used for breast cancer. This medicine is also used for reproductive health in women caused by a failure to produce and release eggs. Breast cancer is a disease in which cells in the breast grow out of control. There are different kinds of breast cancer. The kind of breast cancer depends on which cells in the breast turn into cancer.
Along with this management, your doctor might ask you to make certain lifestyle changes such as eating a healthy diet, healthy sleep habits and managing your weight. Prior to the management, your doctor may want you to take certain breast examinations to understand your existing condition. NOLVADEX is not recommended for use in patients with a history of blood clots (including family).
NOLVADEX should be used with caution in patients with a history of hereditary angioedema. NOLVADEX is not recommended for use in pregnant women. Inform your doctor before taking NOLVADEX if you are breastfeeding. NOLVADEX is not recommended for use in children. The most common side effects of taking NOLVADEX are nausea, fluid retention, skin rash, hot flushes, tiredness and anemia. Consult your doctor if any of the above side effects worsen or persist for a long time.
USES OF NOLVADEX eralefaccommodate patients for management of treatment of treatment of breast cancerHow may I store NOLVADEXThe medicine NOLVADEX is to treat:
NOLVADEX should be stored at room temperature, out of the reach of children and animals. Do not use in cases of heavy or low-dose chemotherapy, including taxane treatment. NOLVADEX should not be taken by women who are pregnant or who may become pregnant. NOLVADEX may cause harm to an pregnant woman, if you are pregnant or planning to become pregnant. NOLVADEX should not be taken by children or adolescents of any gender, because it is used for different types of breast cancer. In any case, keep in your doctor's office.
iffin athotree medicine for management of treatment of breast cancerTablet should not be used while breast forming. Do not take NOLVADEX if you are dehydrated, it may impair your vision. Let the bottle speak first before you use it. It is better to use NOLVADEX when you are getting started with management of breast cancer in adults and in children than to take it after a huge increase in patients' treatment with other anti-estrogens.
SIDE EFFECTS OF NOLVADEX eralefaccommodate patientsMost of the side effects of NOLVADEX are reversible. However, if you develop them stop taking NOLVADEX and call your doctor free of charge. If you have any questions concerning your side effects, call your doctor or get medical attention at once.
Cautions and warnings for NOLVADEX eralefaccommodate patientsStorage of NOLVADEX tablets for use in medical suppliesMolaunch side medicine for management of treatment of breast cancerSome mild to moderate side effects include:
Call your doctor immediately if you experience:
Tamoxifen is a steroid used to treat breast cancer.
Nolvadex is a prescription medication used to treat breast cancer in women who have gone through menopause. The medication is available in the following forms:
It’s important to note that Nolvadex is only effective against breast cancer. In fact, research has found that this drug can be helpful for those who are at risk for developing breast cancer.
Nolvadex is available in two forms:
A brand name version of Nolvadex is Nolvadex-SR, which is sold as a generic version of Tamoxifen.
A version called Nolvadex-DTX is sold as a generic version of Tamoxifen. The brand name Nolvadex-DTX is manufactured by the Tovar Pharmaceutical Company and is available in Canada, India, and the United States. The generic Nolvadex-SR is available in Canada and the United States.
If you are having trouble getting your hands on Nolvadex-SR, you can buy it online in Canada.
Nolvadex is a medication used to treat breast cancer in women who have gone through menopause. The drug is available in the following forms:The drug is available in two forms:A brand name version of Nolvadex is Nolvadex-DTX, which is sold as a generic version of Tamoxifen.Sold and Supplied by Healthylife Pharmacy
This product is a Prescription Only Medicine (S4) and is sold by Healthylife Pharmacy, an independently owned and operated pharmacy business. This prescription product requires a valid Australian script.
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